Alzheimer’s disease announces itself: If you think you are constantly negative, it may increase your risk

There are people who see everything only the Bad. A new study has now found that frequent negative Thinking is due not only a state of mind or a crisis, but in connection with Alzheimer’s disease can be.

Brooding, Worry, and negative thoughts cycle in motion – that’s what happens to most people once in a while, if you have a difficult Phase in life. Who rooms but thinks often and over a longer period of time in negative Patterns, could be suffering from Alzheimer’s or become ill.

The now found researchers in a new study by the University College in London, in the Journal “Alzheimer’s & Dementia“ was published. A Team of scientists to the psychiatrist, Nathalie L. Marchant looked to 292 older adults over 55 years who were physically and mentally healthy, but either of the parents or siblings had suffered from Alzheimer’s.

Psychological examination and brain scans of the participants

The subjects were subjected to over a period of two years mental Tests, to see how you coped with negative situations. In the centre of the investigation, the so-called RNT, &quot was;repetitive negative thinking", so a measurable cognitive process, in which thoughts, Fears from the past and future-turning fears. For years anxiety and depression are considered as risk factors or precursors for Alzheimer’s disease.

Using brain scans (PET), an imaging procedure, give has also been studied whether or not there is Alzheimer’s disease Protein deposits like Tau and Amyloid in the brain. This store already years before the outbreak of the disease there, and ensure that, over time, nerve cells and their Connections to death and cognitive performance slowing down – i.e. language and memory, as well as attention and spatial orientation.

Deposition of Alzheimer’s proteins in the brain in RNT found

This showed up over the four years that the number of test participants, in which frequent negative Thinking, so RNT, it was found, also cognitive dysfunction and memory loss ceased. Responsible for the harmful deposits that were detected in the brain were. "We were able to find out that a higher Level of RNT is associated with a faster decline of cognitive abilities and a deterioration of memory performance within 48 months führt", so the results of the study. "Here, RNT was with the higher deposits of Tau and Amyloid in the brain in connection gebracht".

The study also showed that depression and anxiety can cause cognitive dysfunction, but without the typical deposits in the brain. These could be brought within this study, only with RNT in connection with the set-up, therefore, as a risk factor for Alzheimer’s disease out.

Deposits by RNT or RNT deposits?

According to the researchers, one should note, however, that all of the study participants at increased Alzheimer’s had already a risk, since the disease occurred already in the immediate family (either parents or siblings). Therefore, one cannot apply the results to the total population.

Although the study confirms the hypothesis that RNT associated with a higher risk of Alzheimer’s, it could also behave exactly the opposite. Say: The deposits of Tau and Amyloid could lead to the Occurrence of RNT. In order to clarify the causality clearly, would have to be further and more comprehensive studies performed, the researchers said.

Therefore, let the results not accurately deduce whether a reduction of the RNT can also reduce the risk of developing Alzheimer’s disease. To do this, you should investigate whether measures such as talking therapies or mindfulness exercises, which can reduce the Occurrence of RNT, also have the consequence that there is less of the harmful Protein deposits in the brain.

Forms of dementia

Alzheimer’s disease is the most common, but only a Form of dementia. Other common forms of Lewy body dementia, protein deposits Inside the nerve cells responsible for mental confusion, visual hallucinations, and motor problems. Or Vascular dementia, the causes, unnoticed strokes. The symptoms are those of Alzheimer’s disease in a similar way.

Different forms of Alzheimer’s dementia

  • Most often occurs in the sporadic Form of Alzheimer’s disease on. In this disease, determining genetic and environmental influences in the course. The biggest risk factor is age. But also, the ApoE4 Gene, which is required for the Transport of fatty acids responsible increases the risk of developing a disease.
  • Much less common is the autosomal dominant Form of Alzheimer’s dementia. Characteristic for this Form of Alzheimer’s disease is that the symptoms occur much earlier and faster increase or accumulate.
  • Within a family, multiple people, Alzheimer patients, talk to doctors of a familial Form of Alzheimer’s disease. In this Form, the risk of the blood is increased related to fall ill to Alzheimer’s. While the lifetime risk is normally ten percent, it increased in first-degree Relatives two and a half times (25 percent).

Risk factors for dementia

In General, the following aspects are considered to be risk factors for dementia disease:

  • Age: From the age of 60. The age of the dementia, the frequency doubles every five years
  • Gender: women are more likely to develop dementia at risk than men
  • Genetic factors: So, the effect of a particular variant of the ApoE gene (important for cholesterol transport in the blood) the probability of Alzheimer’s dementia to develop. In carriers of ApoE4 in disease signs and symptoms occur very early.

“About 30 percent of Alzheimer’s risk by seven risk factors, we can influence more or less effective,” says the dementia-researcher Miia Kivipelto from the Karolinska Institute in Stockholm. They are:

  • Diabetes
  • High blood pressure
  • Obesity
  • Lack of exercise
  • Smoking
  • low education
  • Depression

Signs of dementia

The first Phase of the dementia diseases such as Alzheimer’s disease is the stage of mild dementia.

The Patients can not remember new things. In addition, abstract tasks of everyday life to make, such as, for example, a tax return, difficult. In this stage of Alzheimer’s disease in certain areas of the cerebral cortex (neocortex), the first protein formed clumps (Amyloid Beta Plaques).

Is the stage of moderately severe dementia is reached, the clumped proteins already in other areas of the brain affected. The Sufferers can no longer recognize complex shapes and patterns properly and to remember. So it is for patients difficult to operate household appliances or to dress independently. Also, the language suffers from the understanding. The Patients themselves can see their own impairments mostly do not (Anosognosia).

The symptoms increases over time. For the Sufferers often psychological additional symptoms, brings about, such as anxiety, depression, hallucinations, or disturbance of the sleep-Wake rhythm. The stage of severe dementia characterize increasing motor and autonomic disorders, such as incontinence. The Sick are in need of care.

Alzheimer’s disease is not the same for every patient. Recent studies have shown that the protein clumps, which are responsible for the symptoms, come from different protein families. This could be an explanation for the different course of the disease, concluded researchers from the University of California in San Francisco.

Dementia prevention – is it possible?

Depending on the form of Dementia you can prevent it, so better or worse. Compared to some species, we are according to the current state of the science is simply powerless.

Nevertheless: What is the harm your body can also affect the brain. So you can, at least, contrary to a vascular dementia by attention to the following six things:

1. You eat a balanced diet

According to latest research, eating a Mediterranean diet is especially good for our heart and brain. Recently Australian researchers came to the conclusion that with this diet, the dementia way-risk can be lower. The diet is mainly fruits, vegetables, whole grain and milk products, olive oil, little red meat, instead fish and chicken.

2. You drink alcohol only in moderation

Advocates of the Mediterranean diet also recommend a glass of red wine. It should be however. Because heavy alcohol consumption can damage the brain. This is the context that scientists from Stockholm confirmed. Subjects who drank less than once per month alcohol, suffered only half as likely to memory problems, such as test persons drank more often.

The researchers did not distinguish between wine, beer and spirits. Particularly interesting: the subjects, the handles never to alcohol, increased the risk of dementia, in turn, slightly, compared with the Little-drinkers.

3. You to move sufficiently

Australian scientists recommend two and a half hours of Sport per week, in order to curb memory loss. The acting is better than drugs.

4. Indulge yourself in stressful situations, a time-out

Stress can promote the degradation processes in the brain and lead to Alzheimer’s disease, reports researchers from Argentina. They found: Of the 107 studied Alzheimer’s patients, 78 were severely burdened emotionally, such as through the death of a family member, Violence, or accidents.

5. You don’t smoke

Smokers have a twice as high risk of dementia such as non-Smoking. As the result of a long-term study of more than 21,000 US citizens is. Those who want to prevent dementia, you should break the habit of therefore, the Smoking.

6. You regularly go to the Sauna

A study, of course, of Finnish researchers, suggests that sweating can help you in the Sauna in the fight against dementia. The researchers studied more than 2000 healthy men. Those who saunierten four to seven Times a week, had muffles a 66 percent lower risk of dementia compared with a Sauna.

Fear of Alzheimer’s? Your risk can already predict

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