New sleeping pill allow for a safer sleep
Many people have problems with your nighttime sleep. Affected back then, it is not rare to sleep. Such products, however, can have unpleasant side effects. When people are taking prescription sleeping pills, these are not usually so strong that the user Wake up to a fire alarm in the house. New drugs to how to fix this Problem now.
Doctors have warned for a long time already, and that users of prescription sleep run pills risk, even in the case of a fire alarm in the house not to Wake up. Researchers at the Kagoshima University in Japan, investigated a new class of so-called hypnotic drugs that act like sleeping pills, people but during an Emergency, Wake up. The experts published the results of their study in the English journal “Frontiers in Behavioral Neuroscience”.
Half of the subjects responded to a fire alarm
If your house device in the middle of the night in a fire, you want to Wake up safely and quickly out of danger. In the present study, half of the study participants, which prescription sleeping pills fell asleep, in spite of a fire alarm, although this was as loud as if right next to your bed is sucked. The scientists estimate that millions of people are taking prescription sleeping pills like Ambien and Halcion, and would sleep through a fire alarm.
Benzodiazepines suppress different areas of the brain
Benzodiazepines the most commonly prescribed types of sleeping pills, which bring the brain in a so-called sleep mode. Unfortunately, these medicines press different areas of the human brain. This also includes the area of the brain that decides to pay attention to which external information in spite of of sleep, such as noises in the night.
Advantages of hypnotic sleep means
In the last ten years, scientists have developed a new class of hypnotic drugs called Dual Orexin Receptor antagonists (DORAs). Dora’s work targeted to the sleep – and Weckpfade of the brain, causing you to be a safer Alternative to benzodiazepines and at the same time lower negative effects cause. In Tests on laboratory mice, animals in which the benzodiazepine was Triazolam was administered, were slower to awake, compared with mice that were administered DORA-22, explain the authors of the study. For their study, the doctors confronted the animals with the noises of a Fox, a serious threat to a mouse. As soon as the danger was over, went to sleep, the mice, which DORA-22 has been given, as quickly as the mice in which a conventional sleeping pill had been administered. All the animals slept significantly faster than mice, where no sleep was given.
Further research is required
Now further Tests are required to determine whether Dora’s are recommended for use in people as a sleep aid. Since the year 2014 a DORA with the name Surovexant in Japan, the USA and Australia has already received regulatory approval. High cost and limited clinical testing of Surovexant have hindered the use of, but new DORA types that are currently in development, could one day provide better results at a lower cost, experts explain. (as)