Chronic inflammatory bowel diseases are a widespread disease
Chronic inflammatory bowel diseases (IBD) are at the present time the most widespread chronic diseases. In Europe alone, three million people are affected. The majority of patients suffering of ulcerative colitis and Crohn’s disease. What effect does Vitamin D in this disease?
Vitamin-D deficiency as a trigger?
In patients with chronic diseases often a Vitamin-D is found to be deficient, even in patients with chronic inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis. A research team at the Hospital of Jinan in Guangzhou (China) has recently shown in his study that Vitamin D has a positive influence on the intestinal mucosa. This showed less pathological changes, if the Vitamin D supply was better. Was published the study in the journal Medicine.
Vitamin D has a positive effect on the intestinal mucosa
The researchers report that Vitamin D inflammation have anti-inflammatory properties as well as the Regeneration of intestinal mucosa, promotes, and thus, the symptoms and the quality of life of people with chronic inflammatory bowel disease, could improve.
Dosage of Vitamin D
The evaluation showed that the addition of Vitamin D preparations Vitamin D levels reliably increased, but high-dose therapy increased the levels better than the low doses. In the high-dose therapy, doses of 1000 up to 10.000 IU was administered. The researchers explicitly point out that officially, only the intake of daily 600 IU (maximum 4,000 IU), it was recommended that these low doses but for people who already had a deficiency, is not always sufficient.
Side effects of Vitamin D
Side effects were recorded only in a few subjects, and only in the high-dose variant. The researchers stress but in the same breath, that the benefits of this therapy outweigh. In the case of the listed side effects are rather harmless events, such as thirst, Nausea, dry mouth, and fatigue. It is, however, not to say clearly, whether these symptoms are actually due to the Vitamin D intake.
Vitamin D diseases is helpful in chronic inflammatory bowel
It was particularly important in the outcome of the analysis presented that the intake of Vitamin D, the number of relapses. Here, there is no difference between high and low Vitamin D, however, showed doses. Crucial, apparently, was that ever a Supplement with Vitamin D has been thought of. The conclusion of the researchers was that the intake of Vitamin D is recommended to accompany the therapy of chronic inflammatory bowel disease. (fm)